Member's Search

Category: Diagnostics

16/05/2016

Correlation between retinal demage in Age related macular degeneration and cardio-vascular patology in patients with cardio-vascular diseases

Автор
Aleksandrova S.
I Eye Clinic Hospital – Sofia
Рецензент: д-р Христина Видинова д.м.

ABSTRACT

Aim:
To find correspondence between the levels of retinal changes in age related macular degeneration cases and the gravity of the attendant cardiovascular disease.

Method:
Retrospective analysis of macular degeneration patient’s fluorescein angiograms and searching for comorbidity with internal diseases in the electronic archives of the Premier Municipal Hospital for Active Treatment in Sofia for the period November 2011 to June 2015, has been performed. For 31 patients diagnosed with macular degeneration, information for concomitant internal diseases was found. Our further study showed that 10 of the patients had serious cardiac impairments, 8 of them had also significant retinal changes. The patients with the pulmonary diseases had most severe retinal changes. We do not have information for their smoking habits.

Results:
All age related macular degeneration patients for which we found detailed information had arterial hypertension. Correspondence was observed between the severities of the retinal and the cardiovascular changes. The eyes of patients with a pulmonary disease were most significantly affected. The conclusions are not statistically significant because of the size of the group but they are relevant to various multinational studies. We have observations for which we could not find scientific articles worldwide. They will be on the found of our future researches.

LITERATURE

  1. Wong WL, Su X, Li X, Cheung CMG, Klein R, Cheng C-Y, et al. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta- analysis. The Lancet Global Health. 2014;2(2):e106- e16.
  2. Pascolini D, Mariotti SP. Global estimates of visual impairment: 2010. The British journal of oph- thalmology. 2012 May;96(5):614-8. PubMed PMID: 22133988
  3.  The Framingham Eye Study Monograph: An Ophthalmological and Epidemiological Study of Cataract, Glaucoma, Diabetic Retinopathy, Macular Degeneration, and Visual Acuity in a General Popu- lation of 2631 Adults, 1973–1975, Kahn HA, Leibow- itz HM, Ganley JP, Kini MM, Colton T, Nickerson RS, Dawber TR, published by Survey of Ophthalmology (Surv Ophthalmol 24 (suppl): 335–610, 1980)
  4. Pathologies Oculaires Liées à l’Age POLA Study -Cécile Delcourt, PhD; Jean-Paul Cristol, MD; Frédéric Tessier, PhD; Claude L. Léger, PhD;Bernard Descomps, MD; Laure Papoz, PhD; and the POLA Study Group Arch.ophthalmol./vol.117, oct. 1999
  5. Hypertension, Cardiovascular Disease, and Age-Related Macular Degeneration, Leslie Hyman, PhD; Andrew P. Schachat, MD; Qimei He, PhD; M. Cristina Leske, MD, MPH ; for the Age-Related Mac- ular Degeneration Risk Factors Study Group
  6. Arch Ophthalmol. 2000;118(3):351-358. doi:10.1001/archopht.118.3.351.
    Vingerling JRHofman AGrobbee DEde Jong PT Age-related macular degeneration and smoking: the Rotterdam Study. Arch Ophthalmol. 1996;1141193-1196 Link to Article
  7. Smith WMitchell PLeeder SR Smoking and age- related maculopathy: the Blue Mountains Eye Study. Arch Ophthalmol. 1996;1141518- 1523
Posted in Diagnostics, Scientific by Д-р Васил Хайкин | Tags: